Advanced Biochemistry and Biosensors laboratories
Health care is the main area of biosensors applications in recent years. Measurements of analytes in the biological samples are regularly needed to show a patient’s metabolic state especially for those in hospital, and even more so if they are in intensive care. Many of these substrates have been determined by samples of urine and blood being taken away to a medical analytical laboratory for classical analysis, which may not be complete for hours or even days. In emergency cases, an ideal alternative could be on-site biosensors and sensors, a kind of devices, which does not depend on instrumentation and is also rapid, sensitive, specific, cheap, and easy to interpret. The use of on-the-spot biosensors and sensors enable results to be obtained in minutes at most. Therefore our research focus is to develop biosensor and nano-biosensors for rapid and on-site detection of analyte in biological fluids
What is a BIOSENSOR?
A biosensor is a device that incorporates a biological recognition (sensing) element in close proximity or integrated with the signal transducer, to give a reagent less sensing system specific to a target compound (analyte).
Biosensor technology encompasses a wide range of disciplines due to the variety of biological recognition elements and signal transducers used. Typical biological recognition elements used in biosensors range from antibodies, enzyme, affinity ligand (e.g., lectin), receptor, peptide, oligonucleotide, organelle, organism, or tissue slice enzymes. The methods of signal transduction used range from electrical, optical, electrochemical, thermometric, piezoelectric and magnetic.
The research activity at the Biosensors laboratory includes a wide range of projects.
The main areas of interest are:
1- Development of non invasive glucose sensors
2- Development of nano immunosensor and their application in clinical and pharmacological fields.
3- Development of enzyme biosensors and their application in clinical, toxicological and pharmacological fields.
4- Evaluation and optimization of the different immobilization procedures of proteins such as antibody and enzymes and also mediators, which can be used in the development of enzymatic and non enzymatic screen printed electrodes, based biosensors.
5- Development of the optical and electrochemical biosensors using nanotechnologies methods.