Tehran University Of Medical Sciences
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Osteoporosis Research Centre
Osteoporosis Research Center was first established in 1999 as a research group of the Endocrinology and Metabolism Research Center of Tehran University of Medical Sciences. During the past decade, a plethora of research has been carried out on different aspects of osteoporosis by the osteoporosis research team of the EMRI. Considering such prominent achievements, the group was promoted to an affiliated Research Center as soon as the Endocrinology and ...

Osteoporosis, the silent but preventable disease
Due to the overall increase in life expectancy, the prevalence of osteoporosis is increasing. According to the recent report released by the International Osteoporosis Foundation, more than 200 million women suffer from the disease worldwide. Despite the general belief, osteoporosis is not limited to women and a considerable number of men are also affected with the disease.
In view of the fact that osteoporosis remains asymptomatic ...

Pathophysiology:
Three main mechanisms contributing to osteoporosis include: nbspnbsp8226nbsp Failure to achieve the optimum bone strength during the growth and development phases nbspnbsp8226nbsp Excessive absorption of bone which leads to bone mass loss and the destruction of bone structure nbspnbsp8226nbsp Failure to replace the lost bone due to defects in the bone formation process
Estrogen deficiency plays an essential role in the development of osteoporosis. The condition, therefore, is the center of attention in postmenopausal women. Calcium and vitamin D deficiency and secondary hyperparathyroism ...

Definition and Classification of Osteoporosis
Osteoporosis is a systemic skeletal disease characterized by reduced bone density and deterioration of the structure of the bone tissue, leading to bone fragility and an increased susceptibility to fractures. In simpler terms, osteoporosis is a condition in which the bones become weak, fragile and more likely to break even from a minor fall.
Osteoporosis is diagnosed when the bone mineral density is less than or equal to 2.5 standard deviations below that of a young adult reference population. This is translated as a T-score.
The World Health Organization ...
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Pathophysiology

Osteoporosis Research Centre
Osteoporosis Research Center was first established in 1999 as a research group of the Endocrinology and Metabolism Research Center of Tehran University of Medical Sciences. During the past decade, a plethora of research has been carried out on different aspects of osteoporosis by the osteoporosis research team of the EMRI. Considering such prominent achievements, the group was promoted to an affiliated Research Center as soon as the Endocrinology and ...