Tehran University Of Medical Sciences
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About BRC

Biosensor Research Centre
Biosensors have recently emerged and are increasingly utilized as useful instruments in different aspects of health care provision, particularly for diagnosis and monitoring the progress of different diseases. The regular assessment of analyte in biological specimens is required to demonstrate the metabolic states of patients, particularly for those who have been admitted to intensive care. Due to the variety of electrochemically detectable analytes and signal transducers used, biosensor technology encompasses a wide range of disciplines. Typical analytes which are detectable by biosensors from antibodies, enzyme, affinity ligand (e.g., lectin), receptor, ...

What is a biosensor?
The history of biosensors started in the year 1962 with the development of enzyme electrodes by the scientist Leland C. Clark. Since then, research communities from various fields such as VLSI, Physics,Chemistry, and Material Science have come together to develop more sophisticated, reliable and mature biosensing devices for applications in the fields of medicine, agriculture, biotechnology, as well as the military and bioterrorism detection and prevention.
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Basic Concepts
As demonstrated in Fig. 1, a biosensor consists of a bio-element and a sensor-element. The bioelement may be an enzyme, antibody, living cells, tissue, etc., and the sensing element may be electric current,electric potential, and so on. A detailed list of different possible bio-elements and sensor-elements isshown in Fig. 3. Different combinations of bio-elements and sensor-elements constitute several types of biosensors to suit a vast pool of applications. The “bio” ...

Design, preparation and characterization of nanomaterials for sensors and biosensors applications
Quantum Dots with electrochemical properties as well as other nanoparticles with special interest for biosensor applications have been developing. Different methods of synthesis for the production of electroactive nanocrystals (NCs) for use as labels in bioensing systems are being used. They are based on two general ways of controlling the formation and growth of the nanoparticles: ...
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Basic Concepts

Biosensor Research Centre
Biosensors have recently emerged and are increasingly utilized as useful instruments in different aspects of health care provision, particularly for diagnosis and monitoring the progress of different diseases. The regular assessment of analyte in biological specimens is required to demonstrate the metabolic states of patients, particularly for those who have been admitted to intensive care. Due to the variety of electrochemically detectable analytes and signal transducers used, biosensor technology encompasses a wide range of disciplines. Typical analytes which are detectable by biosensors from antibodies, enzyme, affinity ligand (e.g., lectin), receptor, ...