The Endocrinology and Metabolism Research Institute (EMRI), affiliated with Tehran University of Medical Sciences, has established itself as a leading institution dedicated to the comprehensive investigation of diabetes, endocrine disorders, and metabolic diseases. Founded in 1993, EMRI operates under a tripartite mission:

1. Research: Fostering a culture of innovative research to elucidate the underlying mechanisms of these diseases, ultimately accelerating the development of novel therapeutic strategies and potentially curative interventions.
2. Clinical Care: Providing high-quality clinical services for patients suffering from these conditions.
3. Education: Disseminating knowledge and best practices to healthcare professionals and the general public.

EMRI houses three interconnected research institutes, each encompassing a network of specialized research centers. This intricate structure facilitates a collaborative and multidisciplinary approach to research, encompassing a broad spectrum of disciplines:

• Diabetes: This is a major focus, encompassing various aspects such as type 1 and type 2 diabetes, gestational diabetes, diabetic complications, and new treatment modalities including cell therapy and pancreatic transplantation.  
• Osteoporosis: Research on the prevention and treatment of osteoporosis, including bone metabolism and related endocrine factors.
• Obesity and Metabolic Syndrome: Studies on the causes, consequences, and management of obesity and metabolic syndrome, including its relationship with cardiovascular disease.
• Endocrine Cancers: Research into the pathogenesis, diagnosis, and treatment of endocrine-related cancers such as thyroid, adrenal, and pituitary tumors.
• Pediatric Endocrinology: Investigation of endocrine disorders in children and adolescents, including growth disorders, puberty disorders, and diabetes.
• Reproductive Endocrinology: Research on female and male reproductive disorders, infertility, and hormonal imbalances.
• Frailty and Sarcopenia: Investigating the role of endocrine factors in frailty and developing interventions to improve muscle mass and function.
• Cognitive Function and Dementia: Studying the relationship between endocrine disorders and cognitive decline.
• Metabolic Syndrome: A cluster of conditions including high blood pressure, high blood sugar, excess body fat around the waist, and abnormal
• Lipid Disorders: Conditions affecting the body's ability to process fats, including high cholesterol and triglycerides.
• Inborn Errors of Metabolism: Rare genetic disorders that disrupt the body's chemical processes.
• Biosensor: Scientists and engineers at EMRI contribute to the development of innovative biosensors that improve the diagnosis, monitoring, and management of endocrine disorders by addressing research topics, including glucose monitoring, hormone detection, metabolic
• biomarkers, point-of-care (POC) devices, biosensor materials and technologies, and biosensor data analysis.